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Can the KRP1517 PXIe High-Performance Coprocessor support custom logic loading?

Yes, it supports.

The KRP1517 PXIe High-Performance Coprocessor standard with FPGA firmware upgrade software, which supports a convenient dynamic loading function, making it easy for you to load custom logic and algorithms in two ways:

(1) Firmware Upgrade Mode:

By uploading a .kymcs file, the FPGA configuration information is flashed to the KRP1517's onboard Flash for persistent storage. The .kymcs file is a proprietary Kinyea Technologies firmware format, and the standard software allows you to convert your configuration files into the .kymcs format.

(2) Dynamic Configuration Mode:

Configuration is performed over the PCIe bus, which is convenient for online updates and debugging. This mode requires the upload of a .bit file.